Quantitative <sup>31</sup>P NMR Spectroscopy Platform Method for the Assay of Oligonucleotides as Pure Drug Substances and in Drug Product Formulations Using the Internal Standard Method-Reference-Cited by-同舟云学术

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Quantitative ³¹P NMR Spectroscopy Platform Method for the Assay of Oligonucleotides as Pure Drug Substances and in Drug Product Formulations Using the Internal Standard Method

Published:2024-06-29 Issue:28 Volume:96 Page:11198-11204
ISSN:0003-2700
Container-title:Analytical Chemistry
language:en
Short-container-title:Anal. Chem.

Author:

Bjørstorp Simone¹²,Malmstrøm Joan¹^ORCID

Affiliation:

1. Department of CMC Analytical Support, Novo Nordisk A/S, Novo Nordisk Park 1, 2760 Måløv, Denmark

2. Department of Drug Design and Pharmacology, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen Ø, Denmark

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.4c00419

Reference27 articles.

1. Advances in oligonucleotide drug delivery

2. Oligonucleotide therapy: An emerging focus area for drug delivery in chronic inflammatory respiratory diseases

3. Recent developments in the characterization of nucleic acids by liquid chromatography, capillary electrophoresis, ion mobility, and mass spectrometry (2010–2020)

4. Therapeutic siRNA: state of the art

5. Silencing disease genes in the laboratory and the clinic

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