Inverted Sandwich-Type e-LCR Aided by Lambda Exonuclease-RecJf Combination Enables Ultrasensitive Detection of Low-Frequency EGFR-L858R Mutation in NSCLC-Reference-Cited by-同舟云学术

Inverted Sandwich-Type e-LCR Aided by Lambda Exonuclease-RecJf Combination Enables Ultrasensitive Detection of Low-Frequency EGFR-L858R Mutation in NSCLC

Published:2024-08-06 Issue:33 Volume:96 Page:13379-13388
ISSN:0003-2700
Container-title:Analytical Chemistry
language:en
Short-container-title:Anal. Chem.

Author:

Lu Tai-Cheng¹^ORCID,Xu Yi-Quan²,Li Jia-Yi³,Yang Liang-Yong¹^ORCID,Yu Feng-Qiang⁴,Xu Yan-Fang⁵,Liu Ai-Lin³,Chen Jin-Yuan¹^ORCID

Affiliation:

1. The Central Laboratory, Fujian Key Laboratory of Precision Medicine for Cancer, The First Affiliated Hospital, Fujian Medical University, Fuzhou 350005, China

2. Department of Thoracic Oncology, Clinical Oncology School of Fujian Medical University, Fujian Cancer Hospital, Fuzhou 350014, China

3. Department of Pharmaceutical Analysis, Higher Educational Key Laboratory for Nano Biomedical Technology of Fujian Province, The School of Pharmacy, Fujian Medical University, Fuzhou 350122, China

4. Department of Thoracic Surgery, The First Affiliated Hospital, Fujian Medical University, Fuzhou 350005, China

5. Department of Nephrology, The First Affiliated Hospital, Fujian Medical University, Fuzhou 350005, China

Funder

National Natural Science Foundation of China

Joint Funds for the Innovation of Science and Technology, Fujian Province

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.4c00300

Reference36 articles.

1. Device integration of electrochemical biosensors

2. Electrochemical biosensing strategies for DNA methylation analysis

3. Development of Nucleic‐Acid‐Based Electrochemical Biosensors for Clinical Applications

4. Detection of low-frequency mutations in clinical samples by increasing mutation abundance via the excision of wild-type sequences

5. Biomolecular Steric Hindrance Effects Are Enhanced on Nanostructured Microelectrodes