Portable Microfluidic Viscometer for Formulation Development and in Situ Quality Control of Protein and Antibody Solutions-Reference-Cited by-同舟云学术

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Portable Microfluidic Viscometer for Formulation Development and in Situ Quality Control of Protein and Antibody Solutions

Published:2024-08-02 Issue:32 Volume:96 Page:13185-13190
ISSN:0003-2700
Container-title:Analytical Chemistry
language:en
Short-container-title:Anal. Chem.

Author:

Lenzen Philippe S.¹^ORCID,Dingfelder Fabian²,Müller Marius²,Arosio Paolo¹

Affiliation:

1. ETH Zürich, Department of Chemistry and Applied Biosciences, Institute for Chemical and Bioengineering, 8093 Zürich, Switzerland

2. Janssen R&D, BTDS Analytical Development, 8200 Schaffhausen, Switzerland

Funder

Janssen Research and Development

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.4c02099

Reference30 articles.

1. Challenges in the development of high protein concentration formulations

2. Subcutaneous Administration of Biotherapeutics: An Overview of Current Challenges and Opportunities

3. Molecular basis of high viscosity in concentrated antibody solutions: Strategies for high concentration drug product development

4. Specific interactions in high concentration antibody solutions resulting in high viscosity

5. Weak Interactions Govern the Viscosity of Concentrated Antibody Solutions: High-Throughput Analysis Using the Diffusion Interaction Parameter

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