LC/MS/MS Bioanalysis of Protein–Drug Conjugates—The Importance of Incorporating Succinimide Hydrolysis Products

Author:

Shi Chuan1,Goldberg Shalom1,Lin Tricia1,Dudkin Vadim1,Widdison Wayne2,Harris Luke2,Wilhelm Sharon2,Jmeian Yazen1,Davis Darryl1,O’Neil Karyn1,Weng Naidong1,Jian Wenying1ORCID

Affiliation:

1. Janssen Research & Development, LLC, 1400 McKean Road, Spring House, Pennsylvania 19477, United States

2. ImmunoGen, Inc., 830 Winter Street, Waltham, Massachusetts 02451, United States

Publisher

American Chemical Society (ACS)

Subject

Analytical Chemistry

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