Thiol-ene Microfluidic Chip for Performing Hydrogen/Deuterium Exchange of Proteins at Subsecond Time Scales
Author:
Affiliation:
1. Protein Analysis Group, Department of Pharmacy, University of Copenhagen, 2100 Copenhagen, Denmark
2. Microscale Analytical Systems Group, Department of Pharmacy, University of Copenhagen, 2100 Copenhagen, Denmark
Funder
Det Frie Forskningsr?d
H2020 Marie Sklodowska-Curie Actions
Publisher
American Chemical Society (ACS)
Subject
Analytical Chemistry
Link
http://pubs.acs.org/doi/pdf/10.1021/acs.analchem.8b03050
Reference55 articles.
1. Pinpointing changes in higher-order protein structure by hydrogen/deuterium exchange coupled to electron transfer dissociation mass spectrometry
2. Sites Involved in Intra- and Interdomain Allostery Associated with the Activation of Factor VIIa Pinpointed by Hydrogen-Deuterium Exchange and Electron Transfer Dissociation Mass Spectrometry
3. Dissecting the Binding Mode of Low Affinity Phage Display Peptide Ligands to Protein Targets by Hydrogen/Deuterium Exchange Coupled to Mass Spectrometry
4. Time Window Expansion for HDX Analysis of an Intrinsically Disordered Protein
5. Identification of the protein kinase A regulatory RI -catalytic subunit interface by amide H/2H exchange and protein docking
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