Development of Comprehensive Online Two-Dimensional Liquid Chromatography/Mass Spectrometry Using Hydrophilic Interaction and Reversed-Phase Separations for Rapid and Deep Profiling of Therapeutic Antibodies

Author:

Stoll Dwight R.1ORCID,Harmes David C.1,Staples Gregory O.2,Potter Oscar G.2,Dammann Carston T.1,Guillarme Davy3,Beck Alain4

Affiliation:

1. Department of Chemistry, Gustavus Adolphus College, St. Peter, Minnesota 56082, United States

2. Agilent Technologies, Santa Clara, California 95051, United States

3. School of Pharmaceutical Sciences, University of Geneva and University of Lausanne, Rue Michel Servet 1, 1206 Geneva 4, Switzerland

4. Institut de Recherche Pierre Fabre, Center of Immunology, Pierre Fabre, 5, Avenue Napoléon III, BP 60497, 74160 Saint-Julien-en-Genevois, France

Funder

Division of Chemistry

Schweizerischer Nationalfonds zur F?rderung der Wissenschaftlichen Forschung

Agilent Technologies

Publisher

American Chemical Society (ACS)

Subject

Analytical Chemistry

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