Analysis of Megadalton-Sized DNA by Charge Detection Mass Spectrometry: Entropic Trapping and Shearing in Nanoelectrospray
Author:
Affiliation:
1. Chemistry Department, Indiana University, 800 E Kirkwood Ave, Bloomington, Indiana 47405, United States
2. Megadalton Solutions Inc, 3750 E Bluebird Ln, Bloomington, Indiana 47401, United States
Funder
Pfizer
Publisher
American Chemical Society (ACS)
Subject
Analytical Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.3c01027
Reference59 articles.
1. Mass spectrometry of nucleic acids
2. DNA analysis by mass spectrometry—past, present and future
3. Improved electrospray ionization of synthetic oligodeoxynucleotides
4. Electrospray Ionization Mass Spectrometry of Oligonucleotides
5. Analysis of AAV-Extracted DNA by Charge Detection Mass Spectrometry Reveals Genome Truncations
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1. Charge Detection Mass Spectrometry Enables Molecular Characterization of Nucleic Acid Nanoparticles;ACS Nano;2024-08-16
2. Compaction, Relaxation, and Linearization of Megadalton-Sized DNA Plasmids: DNA Structures Probed by CD-MS;Journal of the American Society for Mass Spectrometry;2024-07-16
3. Charge Detection Mass Spectrometry for Megadalton Polymer Characterization and Measurement of Electrospray-Generated Charged Droplet Dynamics with a New “Direct Visualization of the Rayleigh Limit” Approach to Aid in m/z Calibration;Analytical Chemistry;2024-04-23
4. Exploring Charge-Detection Mass Spectrometry on Chromatographic Time Scales;Analytical Chemistry;2023-09-29
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