High-Throughput and Format-Agnostic Mispairing Assay for Multispecific Antibodies Using Intact Mass Spectrometry-Reference-Cited by-同舟云学术

High-Throughput and Format-Agnostic Mispairing Assay for Multispecific Antibodies Using Intact Mass Spectrometry

Published:2023-06-27 Issue:27 Volume:95 Page:10265-10278
ISSN:0003-2700
Container-title:Analytical Chemistry
language:en
Short-container-title:Anal. Chem.

Author:

Ziegengeist Tanja¹,Orth Jennifer¹,Kroll Katja¹,Schneider Marion¹,Spindler Nadja¹,Dimova Dilyana¹,Handschuh Severin¹,Brandenburg Arnd²,Ossola Reto²,Furtmann Norbert¹,Birkenfeld Joerg¹³,Beil Christian¹,Hoffmann Dietmar⁴,Schmidt Thorsten¹,Sendak Rebecca⁴,Fischer Melanie¹,Hölper Soraya¹,Kühn Jennifer¹^ORCID

Affiliation:

1. Large Molecules Research Platform, Sanofi-Aventis Deutschland GmbH, Frankfurt 65926, Germany

2. Genedata AG, Basel 4053, Switzerland

3. Perspix Biotech GmbH FiZ Frankfurt Innovation Center Biotechnology, Frankfurt 60438, Germany

4. Large Molecules Research Platform, Sanofi, Cambridge, Massachusetts 02141, United States

Publisher

American Chemical Society (ACS)

Subject

Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.3c00742

Reference68 articles.

1. Bispecific antibodies: a mechanistic review of the pipeline

2. Properties of the Major Component of a Peptic Digest of Rabbit Antibody

3. Expanding the Boundaries of Biotherapeutics with Bispecific Antibodies

4. Bispecific antibodies: design, therapy, perspectives

5. Catumaxomab

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