Expedited Evaluation of Conformational Stability–Heterogeneity Associations for Crude Polyclonal Antibodies in Response to Conjugate Vaccines

Author:

Zheng Zhen12,Ma Min3,Jia Yifei1,Cui Yusi4,Zhao Rui1,Li Shuangshuang2,Wenthur Cody3,Li Lingjun345ORCID,Li Gongyu16ORCID

Affiliation:

1. State Key Laboratory of Medicinal Chemical Biology, Tianjin Key Laboratory of Biosensing and Molecular Recognition, Research Center for Analytical Science, Frontiers Science Center for New Organic Matter, College of Chemistry, Nankai University, Tianjin 300071, China

2. School of Pharmacy, Tianjin Medical University, Tianjin 300070, China

3. School of Pharmacy, University of Wisconsin-Madison, Madison, Wisconsin 53705, United States

4. Department of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53705, United States

5. Lachman Institute for Pharmaceutical Development, School of Pharmacy, University of Wisconsin-Madison, Madison, Wisconsin 53705, United States

6. Haihe Laboratory of Sustainable Chemical Transformations, Tianjin 300192, China

Funder

Division of Chemistry

National Institute of Diabetes and Digestive and Kidney Diseases

National Institute on Aging

Fundamental Research Funds for the Central Universities

National Institute of Mental Health

National Natural Science Foundation of China

Haihe Laboratory of Sustainable Chemical Transformations, Nankai University

Publisher

American Chemical Society (ACS)

Subject

Analytical Chemistry

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