Differentiation of Aspartic and Isoaspartic Acid Using 193 nm Ultraviolet Photodissociation Mass Spectrometry-Reference-Cited by-同舟云学术

Differentiation of Aspartic and Isoaspartic Acid Using 193 nm Ultraviolet Photodissociation Mass Spectrometry

Published:2023-07-17 Issue:30 Volume:95 Page:11510-11517
ISSN:0003-2700
Container-title:Analytical Chemistry
language:en
Short-container-title:Anal. Chem.

Author:

Bashyal Aarti¹^ORCID,Hui John O.²^ORCID,Flick Tawnya³,Dykstra Andrew B.³^ORCID,Zhang Qingchun³,Campuzano Iain D. G.²^ORCID,Brodbelt Jennifer S.¹^ORCID

Affiliation:

1. Department of Chemistry, University of Texas at Austin, Austin, Texas 78712, United States

2. Amgen Research, Molecular Analytics, Amgen Inc., Thousand Oaks, California 91320, United States

3. Process Development, Attribute Sciences, Amgen Inc., Thousand Oaks, California 91320, United States

Funder

Welch Foundation

National Institutes of Health

Publisher

American Chemical Society (ACS)

Subject

Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.3c02025

Reference59 articles.

1. Isoaspartate Formation and Neurodegeneration in Alzheimer's Disease

2. Deamidation and isoaspartate formation in proteins: unwanted alterations or surreptitious signals?

3. Mass spectrometric analysis of asparagine deamidation and aspartate isomerization in polypeptides

4. Differentiation of peptide isomers and epimers by radical-directed dissociation

5. The etiology of human age-related cataract. Proteins don't last forever

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