Novel Structure-Driven Predict-to-Hit Strategy for PC Double Bond Positional Isomer Identification Based on Negative LC-MRM Analysis-Reference-Cited by-同舟云学术

Novel Structure-Driven Predict-to-Hit Strategy for PC Double Bond Positional Isomer Identification Based on Negative LC-MRM Analysis

Published:2024-02-08 Issue: Volume: Page:
ISSN:0003-2700
Container-title:Analytical Chemistry
language:en
Short-container-title:Anal. Chem.

Author:

Tie Cai¹²,Cui Xinge³^ORCID,Zhang Zhijun²,Geng Yicong²,Liu Ting⁴,Rong Xiaojuan⁵,Zheng Xin³

Affiliation:

1. State Key Laboratory for Fine Exploration and Intelligent Development of Coal Resources, Ding 11 Xueyuan Road, Beijing 100083, China

2. School of Chemical and Environmental Engineering, China University of Mining and Technology-Beijing, Ding 11 Xueyuan Road, Beijing 100083, China

3. Clinical Pharmacology Research Center, Peking Union Medical College Hospital, State Key Laboratory of Complex Severe and Rare Diseases, NMPA Key Laboratory for Clinical Research and Evaluation of Drug, Beijing Key Laboratory of Clinical PK & PD Investigation for Innovative Drugs, Chinese Academy of Medical Sciences & Peking Union Medical College, No.1 Shuaifuyuan Wangfujing, Dongcheng District, Beijing 100730, China

4. SCIEX, Analytical Instrument Trading Co., Ltd., 518 North Fuquan Road, Shanghai 200335, China

5. Xinjiang Institute of Material Medica, 140 North Xinhua Road, Urumqi, Xinjiang 830004, China

Funder

Fundamental Research Funds for the Central Universities

National High Level Hospital Clinical Research Funding

State Key Laboratory Coal Resources and Safe Mining

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.3c04032

Reference50 articles.

1. The critical role of phosphatidylcholine and phosphatidylethanolamine metabolism in health and disease

2. Intestinal Microbial Metabolism of Phosphatidylcholine and Cardiovascular Risk

3. Evidence of altered phosphatidylcholine metabolism in Alzheimer's disease

4. MARC1 variant rs2642438 increases hepatic phosphatidylcholines and decreases severity of non-alcoholic fatty liver disease in humans

5. Phosphatidylcholine-Derived Lipid Mediators: The Crosstalk Between Cancer Cells and Immune Cells