Nanobody-Based Quantification of GTP-Bound RHO Conformation Reveals RHOA and RHOC Activation Independent from Their Total Expression in Breast Cancer-Reference-Cited by-同舟云学术

Nanobody-Based Quantification of GTP-Bound RHO Conformation Reveals RHOA and RHOC Activation Independent from Their Total Expression in Breast Cancer

Published:2021-04-07 Issue:15 Volume:93 Page:6104-6111
ISSN:0003-2700
Container-title:Analytical Chemistry
language:en
Short-container-title:Anal. Chem.

Author:

Keller Laura¹²,Tardy Claudine¹,Ligat Laetitia³,Gilhodes Julia⁴,Filleron Thomas⁴,Bery Nicolas¹,Rochaix Philippe²,Aquilina Alexis⁵,Bdioui Sara⁵,Roux Thomas⁵,Trinquet Eric⁵,Favre Gilles¹²,Olichon Aurélien¹⁶^ORCID

Affiliation:

1. Centre de Recherche en Cancérologie de Toulouse (CRCT), INSERM, Université de Toulouse, CNRS, UPS, Toulouse 31037, France

2. Laboratoire de Biologie Médicale Oncologique, Institut Claudius Regaud, IUCT-Oncopôle, Toulouse 31037, France

3. Le Pôle Technologique du Centre de Recherches en Cancérologie de Toulouse, plateau de protéomique, Toulouse 31037, France

4. Service de Biostatistiques, Institut Claudius Regaud, IUCT-Oncopôle, Toulouse 31059, France

5. Cisbio Bioassays, Codolet 31059, France

6. INSERM, UMR 1188 Diabète athérothrombose Réunion Océan Indien (DéTROI), Université de La Réunion, Saint-Denis de La Réunion 97487, France

Funder

Fondation pour la Recherche M?dicale

Publisher

American Chemical Society (ACS)

Subject

Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.0c05137

Reference45 articles.

1. Rho GTPases in transformation and metastasis

2. Rho GTPases in cancer cell biology

3. Rho GTPases in human breast tumours: expression and mutation analyses and correlation with clinical parameters

4. Up-Regulation of Small GTPases, RhoA and RhoC, Is Associated with Tumor Progression in Ovarian Carcinoma

5. Paving the Rho in cancer metastasis: Rho GTPases and beyond

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