1. Centre for Biologics Evaluation, Biologics and Genetic Therapies Directorate, Health Canada, 251 Sir Frederick Banting, Tunney’s Pasture, Ottawa, Ontario K1A 0K9, Canada
2. National Research Council Canada, Human Health Therapeutics Research Centre, Ottawa, Ontario K1A 0R6, Canada
3. National Institutes for Food and Drug Control and WHO Collaborating Center for Standardization and Evaluation of Biologicals, National Institute for Food and Drug Control of China, No.2 Tiantan Xili, Beijing 10050, People’s Republic of China
4. Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Ontario K1H 8M5, Canada