Uniformly 15N-Labeled Recombinant Ricin A-Chain as an Internal Retention Time Standard for Increased Confidence in Forensic Identification of Ricin by Untargeted Nanoflow Liquid Chromatography-Tandem Mass Spectrometry-Reference-Cited by-同舟云学术

Uniformly 15N-Labeled Recombinant Ricin A-Chain as an Internal Retention Time Standard for Increased Confidence in Forensic Identification of Ricin by Untargeted Nanoflow Liquid Chromatography-Tandem Mass Spectrometry

Published:2019-10-09 Issue:21 Volume:91 Page:13372-13376
ISSN:0003-2700
Container-title:Analytical Chemistry
language:en
Short-container-title:Anal. Chem.

Author:

Merkley Eric D.¹^ORCID,Burnum-Johnson Kristin E.²^ORCID,Anderson Lindsey N.³,Jenson Sarah C.¹,Wahl Karen L.²

Affiliation:

1. Chemical and Biological Signature Sciences Group, Pacific Northwest National Laboratory, Richland, Washington 99354, United States

2. Integrative Omics Group, Pacific Northwest National Laboratory, Richland, Washington 99354, United States

3. Biological Systems Science Group, Pacific Northwest National Laboratory, Richland, Washington 99354, United States

Funder

Science and Technology Directorate

Publisher

American Chemical Society (ACS)

Subject

Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.9b03389

Reference31 articles.

1. Ricin detection: Tracking active toxin

2. Ricin poisoning and forensic toxicology

4. Proteomic Methods of Detection and Quantification of Protein Toxins

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1. Ricin and other toxalbumins;Encyclopedia of Toxicology;2024

2. A protein standard absolute quantification strategy for enhanced absolute quantification of ricin in complex matrices using in vitro synthesized mutant holoprotein as internal standard by ultra-high-performance liquid chromatography-tandem mass spectrometry;Journal of Chromatography A;2023-10

3. Miniaturized LC in Molecular Omics;Analytical Chemistry;2020-08-12