Ratio-Based Method To Identify True Biomarkers by Normalizing Circulating ncRNA Sequencing and Quantitative PCR Data

Author:

Deng Youping1ORCID,Zhu Yong2,Wang Hongwei3,Khadka Vedbar S.1,Hu Ling4,Ai Junmei5,Dou Yuhong56,Li Yan5,Dai Shengming17,Mason Christopher E.8,Wang Yunliang9,Jia Wei10ORCID,Zhang Jicai11,Huang Gang12,Jiang Bin2

Affiliation:

1. Bioinformatics Core, Department of Complementary & Integrative Medicine, University of Hawaii John A. Burns School of Medicine, Honolulu, Hawaii 96813, United States

2. National Center of Colorectal Disease, Nanjing Municipal Hospital of Chinese Medicine, the Third Affiliated Hospital, Nanjing University of Chinese Medicine, Nanjing 210001, P. R. China

3. University of Chicago, Chicago, Illinois 60637, United States

4. Department of Anesthesiology, Tianyou Hospital, Wuhan University of Science and Technology, Wuhan 430064, P. R. China

5. Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois 60612, United States

6. Department of Clinical Laboratory, Shenzhen Shajing Affiliated Hospital of Guangzhou Medical University, Shenzhen 518104, P. R. China

7. Medical Science Laboratory, The Fourth Affiliated Hospital of Guangxi Medical University, Liuzhou, Guangxi 545005, P. R. China

8. Department of Physiology and Biophysics and the Institute for Computational Biomedicine, Weill Cornell Medical College, New York, New York 10065, United States

9. Department of Neurology, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450008, P. R. China

10. University of Hawaii Cancer Center, Honolulu, Hawaii 96813, United States

11. Department of Laboratory Medicine, Shiyan Taihe Hospital, College of Biomedical Engineering, Hubei University of Medicine, Shiyan, Hubei 442000, P. R. China

12. Shanghai Key Laboratory for Molecular Imaging, Shanghai University of Medicine and Health Sciences, Shanghai 201318, P. R. China

Funder

Hawaii Community Foundation

National Institutes of Health

Publisher

American Chemical Society (ACS)

Subject

Analytical Chemistry

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