Complete Extraction of Protein Dynamics Information in Hydrogen/Deuterium Exchange Mass Spectrometry Data
Author:
Affiliation:
1. Process Development, Amgen Incorporated, One Amgen Center Drive, Thousand Oaks, California 91320, United States
Funder
Amgen
Publisher
American Chemical Society (ACS)
Subject
Analytical Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.9b05724
Reference41 articles.
1. Determination of amide hydrogen exchange by mass spectrometry: A new tool for protein structure elucidation
2. Conformational analysis of complex protein states by hydrogen/deuterium exchange mass spectrometry (HDX-MS): Challenges and emerging solutions
3. Higher order structure characterization of protein therapeutics by hydrogen/deuterium exchange mass spectrometry
4. HDX-MS guided drug discovery: small molecules and biopharmaceuticals
5. Hydrogen-Deuterium Exchange Mass Spectrometry as an Emerging Analytical Tool for Stabilization and Formulation Development of Therapeutic Monoclonal Antibodies
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