Comparative Glycomic Analysis of Sialyl Linkage Isomers by Sialic Acid Linkage-Specific Alkylamidation in Combination with Stable Isotope Labeling of α2,3-Linked Sialic Acid Residues

Author:

Hanamatsu Hisatoshi12,Nishikaze Takashi3ORCID,Tsumoto Hiroki4,Ogawa Koji1,Kobayashi Takashi5ORCID,Yokota Ikuko2,Morikawa Kenichi1,Suda Goki1,Sho Takuya1,Nakai Masato1,Miura Nobuaki6,Higashino Kenichi5,Sekiya Sadanori3,Iwamoto Shinichi3,Miura Yuri4ORCID,Furukawa Jun-ichi2ORCID,Tanaka Koichi3,Sakamoto Naoya1

Affiliation:

1. Department of Gastroenterology and Hepatology, Graduate School of Medicine, Hokkaido University, Sapporo, Hokkaido 060-8638, Japan

2. Department of Advanced Clinical Glycobiology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Hokkaido 001-0021, Japan

3. Koichi Tanaka Mass Spectrometry Research Laboratory, Shimadzu Corporation, Kyoto, Kyoto 604-8511, Japan

4. Research Team for Mechanism of Aging, Tokyo Metropolitan Institute of Gerontology, Tokyo 173-0015, Japan

5. Shionogi Innovation Center for Drug Discovery, Shionogi & Co., Ltd., Sapporo, Hokkaido 001-0021, Japan

6. Bioinformatics Laboratory, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Niigata 951-8510, Japan

Funder

Japan Agency for Medical Research and Development

Japan Society for the Promotion of Science

Sumitomo Electric Industries Ltd. (SEI), the Group CSR Foundation

Publisher

American Chemical Society (ACS)

Subject

Analytical Chemistry

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