Fast Pathogen Identification Using Single-Cell Matrix-Assisted Laser Desorption/Ionization-Aerosol Time-of-Flight Mass Spectrometry Data and Deep Learning Methods
Author:
Affiliation:
1. Department of Data Analysis and Mathematical Modelling, Ghent University, Ghent 9000, Belgium
2. BiosparQ B.V., Leiden 2333 BD, The Netherlands
3. Flanders Marine Institute (VLIZ), Ostend 8400, Belgium
Funder
Vlaamse regering
BiosparQ
Publisher
American Chemical Society (ACS)
Subject
Analytical Chemistry
Link
http://pubs.acs.org/doi/pdf/10.1021/acs.analchem.9b05806
Reference44 articles.
1. Progress in proteomics for clinical microbiology: MALDI-TOF MS for microbial species identification and more
2. Prospective Evaluation of a Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry System in a Hospital Clinical Microbiology Laboratory for Identification of Bacteria and Yeasts: a Bench-by-Bench Study for Assessing the Impact on Time to Identification and Cost-Effectiveness
3. Direct Identification of Urinary Tract Pathogens from Urine Samples by Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry
4. Rapid Identification and Antimicrobial Susceptibility Testing for Urinary Tract Pathogens by Direct Analysis of Urine Samples Using a MALDI-TOF MS-Based Combined Protocol
5. Direct application of MALDI-TOF mass spectrometry to cerebrospinal fluid for rapid pathogen identification in a patient with bacterial meningitis
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