An Integrated Approach for Determining a Protein–Protein Binding Interface in Solution and an Evaluation of Hydrogen–Deuterium Exchange Kinetics for Adjudicating Candidate Docking Models-Reference-Cited by-同舟云学术

An Integrated Approach for Determining a Protein–Protein Binding Interface in Solution and an Evaluation of Hydrogen–Deuterium Exchange Kinetics for Adjudicating Candidate Docking Models

Published:2019-11-11 Issue:24 Volume:91 Page:15709-15717
ISSN:0003-2700
Container-title:Analytical Chemistry
language:en
Short-container-title:Anal. Chem.

Author:

Zhang Mengru Mira¹^ORCID,Beno Brett R.²,Huang Richard Y.-C.³^ORCID,Adhikari Jagat¹^ORCID,Deyanova Ekaterina G.³,Li Jing³,Chen Guodong³^ORCID,Gross Michael L.¹^ORCID

Affiliation:

1. Department of Chemistry, Washington University, St. Louis, Missouri 63130, United States

2. Molecular Structure & Design, Molecular Discovery Technologies, Research and Development, Bristol-Myers Squibb, Princeton, New Jersey 08540, United States

3. Pharmaceutical Candidate Optimization, Research and Development, Bristol-Myers Squibb Company, Princeton, New Jersey 08540, United States

Funder

Bristol-Myers Squibb

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.9b03879

Reference53 articles.

1. Protein interaction networks in innate immunity