Characterization of the Impact of Drug Metabolism on the Gas-Phase Structures of Drugs Using Ion Mobility-Mass Spectrometry-Reference-Cited by-同舟云学术

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Characterization of the Impact of Drug Metabolism on the Gas-Phase Structures of Drugs Using Ion Mobility-Mass Spectrometry

Published:2019-10-15 Issue:22 Volume:91 Page:14498-14507
ISSN:0003-2700
Container-title:Analytical Chemistry
language:en
Short-container-title:Anal. Chem.

Author:

Ross Dylan H.¹,Seguin Ryan P.¹,Xu Libin¹^ORCID

Affiliation:

1. Department of Medicinal Chemistry, University of Washington, Seattle, Washington 98195, United States

Funder

National Institute of Environmental Health Sciences

University of Washington

National Institute of Child Health and Human Development

National Institute of General Medical Sciences

Department of Medicinal Chemistry, University of Washington

Publisher

American Chemical Society (ACS)

Subject

Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.9b03292

Reference49 articles.

1. Cytochrome P450 enzymes in drug metabolism: Regulation of gene expression, enzyme activities, and impact of genetic variation

2. Glutathione transferases, regulators of cellular metabolism and physiology

3. Human UDP-Glucuronosyltransferases: Metabolism, Expression, and Disease

4. Discovering Drugs through Biological Transformation: Role of Pharmacologically Active Metabolites in Drug Discovery

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