Discovery of AHCY as an Off-Target of Doxorubicin by Integrative Analysis of Photoaffinity Labeling Chemoproteomics and Untargeted Metabolomics-Reference-Cited by-同舟云学术

Discovery of AHCY as an Off-Target of Doxorubicin by Integrative Analysis of Photoaffinity Labeling Chemoproteomics and Untargeted Metabolomics

Published:2022-11-29 Issue:49 Volume:94 Page:17121-17130
ISSN:0003-2700
Container-title:Analytical Chemistry
language:en
Short-container-title:Anal. Chem.

Author:

Qian Shanshan¹²,Han Ying³,Zhang Yue¹²,Du Yanan¹⁴,Li Jing¹⁴,Yang Xin¹⁴,Kang Jingwu¹⁴^ORCID

Affiliation:

1. State Key Laboratory of Bioorganic and Natural Products Chemistry, Center for Excellence in Molecular Synthesis, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai200032, China

2. University of Chinese Academy of Sciences, Yuquan Road 19, Beijing100049, China

3. School of Life Science and Technology, ShanghaiTech University, Haike Road 100, Shanghai200120, China

4. School of Physical Science and Technology, ShanghaiTech University, Haike Road 100, Shanghai200120, China

Funder

National Natural Science Foundation of China

Chinese Academy of Sciences

Publisher

American Chemical Society (ACS)

Subject

Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.2c03377

Reference36 articles.

1. The cellular response to drug perturbation is limited: comparison of large-scale chemogenomic fitness signatures

2. Mapping the Cellular Response to Small Molecules Using Chemogenomic Fitness Signatures

3. Applications of chemogenomic library screening in drug discovery

4. Mass-spectrometric exploration of proteome structure and function

5. Target profiling of small molecules by chemical proteomics

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