Novel Strategy to Rapidly Profile and Identify Oxidized Species of Polysorbate 80 Using Ultra-High-Performance Liquid Chromatography Coupled with High-Resolution Mass Spectrometry-Reference-Cited by-同舟云学术

Novel Strategy to Rapidly Profile and Identify Oxidized Species of Polysorbate 80 Using Ultra-High-Performance Liquid Chromatography Coupled with High-Resolution Mass Spectrometry

Published:2023-05-30 Issue:24 Volume:95 Page:9156-9163
ISSN:0003-2700
Container-title:Analytical Chemistry
language:en
Short-container-title:Anal. Chem.

Author:

Li Xinjian¹,Wang Zhe¹,Zheng Bowen¹,Wang Yanan¹^ORCID,Zhang Jinlan¹^ORCID

Affiliation:

1. State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing 100050, P.R. China

Funder

Chinese Academy of Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.2c04956

Reference35 articles.

1. Rational design to biologics development: The polysorbates point of view

2. Polysorbates 20 and 80 Used in the Formulation of Protein Biotherapeutics: Structure and Degradation Pathways

3. Fluorescent Molecular Rotors as Dyes to Characterize Polysorbate-Containing IgG Formulations