Derivatization of N-Acyl Glycines by 3-Nitrophenylhydrazine for Targeted Metabolomics Analysis and Their Application to the Study of Diabetes Progression in Mice-Reference-Cited by-同舟云学术

Derivatization of N-Acyl Glycines by 3-Nitrophenylhydrazine for Targeted Metabolomics Analysis and Their Application to the Study of Diabetes Progression in Mice

Published:2023-01-19 Issue:4 Volume:95 Page:2183-2191
ISSN:0003-2700
Container-title:Analytical Chemistry
language:en
Short-container-title:Anal. Chem.

Author:

Xiang Li¹,Ru Yi¹,Shi Jingchun¹,Wang Li²,Zhao Hongzhi³,Huang Yu²,Cai Zongwei¹^ORCID

Affiliation:

1. State Key Laboratory of Environmental and Biological Analysis, Department of Chemistry, Hong Kong Baptist University, Hong Kong 999077, China

2. Department of Biomedical Sciences, City University of Hong Kong, Hong Kong 999077, China

3. Ministry of Education Key Laboratory of Pollution Processes and Environmental Criteria, College of Environmental Science and Engineering, Nankai University, Tianjin 300350, China

Funder

Research Grants Council, University Grants Committee

Publisher

American Chemical Society (ACS)

Subject

Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.2c02507

Reference38 articles.

1. A new perspective on the importance of glycine conjugation in the metabolism of aromatic acids

2. Conservation of the coding regions of the glycine N-acyltransferase gene further suggests that glycine conjugation is an essential detoxification pathway

3. Discovery of early-stage biomarkers for diabetic kidney disease using ms-based metabolomics (FinnDiane study)