Liquid Chromatography–Mass Spectrometry-Based Qualitative Profiling of mRNA Therapeutic Reagents Using Stable Isotope-Labeled Standards Followed by the Automatic Quantitation Software Ariadne
Author:
Affiliation:
1. Biomolecular Characterization Unit, RIKEN Center for Sustainable Resource Science, Wako-shi, Saitama 351-0198, Japan
2. Department of Chemistry, Graduate School of Science, Tokyo Metropolitan University, Hachioji-shi, Tokyo 192-0397, Japan
Publisher
American Chemical Society (ACS)
Subject
Analytical Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.2c04323
Reference41 articles.
1. mRNA therapeutics in cancer immunotherapy
2. mRNA-based therapeutics: powerful and versatile tools to combat diseases
3. The clinical progress of mRNA vaccines and immunotherapies
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5. mRNA vaccines — a new era in vaccinology
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1. Selective Characterization of mRNA 5′ End-Capping by DNA Probe-Directed Enrichment with Site-Specific Endoribonucleases;ACS Pharmacology & Translational Science;2023-10-18
2. Oligonucleotide mapping via mass spectrometry to enable comprehensive primary structure characterization of an mRNA vaccine against SARS-CoV-2;Scientific Reports;2023-06-03
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