Parahydrogen in Reversible Exchange Induces Long-Lived <sup>15</sup>N Hyperpolarization of Anticancer Drugs Anastrozole and Letrozole-Reference-Cited by-同舟云学术

Parahydrogen in Reversible Exchange Induces Long-Lived ¹⁵N Hyperpolarization of Anticancer Drugs Anastrozole and Letrozole

Published:2023-05-10 Issue:20 Volume:95 Page:7822-7829
ISSN:0003-2700
Container-title:Analytical Chemistry
language:en
Short-container-title:Anal. Chem.

Author:

MacCulloch Keilian¹^ORCID,Browning Austin¹,TomHon Patrick¹^ORCID,Lehmkuhl Sören¹^ORCID,Chekmenev Eduard Y.²³⁴^ORCID,Theis Thomas¹⁵⁶^ORCID

Affiliation:

1. Department of Chemistry, North Carolina State University, Raleigh, North Carolina 27606, United States

2. Department of Chemistry, Wayne State University, Detroit, Michigan 48202, United States

3. Integrative Biosciences (Ibio), Wayne State University, Karmanos Cancer Institute (KCI), Detroit, Michigan 48202, United States

4. Russian Academy of Sciences, Leninskiy Prospekt 14, 119991 Moscow, Russia

5. Joint Department of Biomedical Engineering, University of North Carolina, Chapel Hill and North Carolina State University, Raleigh, North Carolina 27606, United States

6. Department of Physics, North Carolina State University, Raleigh, North Carolina 27606, United States

Funder

Division of Chemistry

National Cancer Institute

National Institute of Biomedical Imaging and Bioengineering

North Carolina Biotechnology Center

Edward Mallinckrodt, Jr. Foundation

Publisher

American Chemical Society (ACS)

Subject

Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.2c04817

Reference90 articles.

1. Hyperpolarized Water to Study Protein–Ligand Interactions

2. Amplification of Nuclear Overhauser Effect Signals by Hyperpolarization for Screening of Ligand Binding to Immobilized Target Proteins

3. Polarization Transfer from Ligands Hyperpolarized by Dissolution Dynamic Nuclear Polarization for Screening in Drug Discovery

4. Generating contrast in hyperpolarized 13C MRI using ligand–receptor interactions

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