Isolation and Characterization of Monoclonal Antibody Charge Variants by Free Flow Isoelectric Focusing-Reference-Cited by-同舟云学术

Isolation and Characterization of Monoclonal Antibody Charge Variants by Free Flow Isoelectric Focusing

Published:2016-05-23 Issue:11 Volume:88 Page:5662-5669
ISSN:0003-2700
Container-title:Analytical Chemistry
language:en
Short-container-title:Anal. Chem.

Author:

Hosken Brian D.¹,Li Charlene¹,Mullappally Berny¹,Co Carl¹,Zhang Boyan¹

Affiliation:

1. Department of Protein Analytical Chemistry, ‡Department of Biological Technologies, Genentech, 1 DNA Way, South San Francisco, California 94080, United States

Publisher

American Chemical Society (ACS)

Subject

Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.5b03946

Reference40 articles.

1. Current and future issues in the manufacturing and development of monoclonal antibodies

2. Identification of multiple sources of charge heterogeneity in a recombinant antibody

3. Characterization of Recombinant Human Monoclonal Tissue Necrosis Factor-α Antibody Using Cation-Exchange HPLC and Capillary Isoelectric Focusing

4. Improving pH gradient cation-exchange chromatography of monoclonal antibodies by controlling ionic strength

5. Analysis of charge heterogeneities in mAbs using imaged CE

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