Discovery of Selective Small Molecule Type III Phosphatidylinositol 4-Kinase Alpha (PI4KIIIα) Inhibitors as Anti Hepatitis C (HCV) Agents-Reference-Cited by-同舟云学术

Discovery of Selective Small Molecule Type III Phosphatidylinositol 4-Kinase Alpha (PI4KIIIα) Inhibitors as Anti Hepatitis C (HCV) Agents

Published:2013-08-14 Issue:5 Volume:57 Page:2091-2106
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Leivers Anna L.¹,Tallant Matthew¹,Shotwell J. Brad¹,Dickerson Scott²,Leivers Martin R.¹,McDonald Octerloney B.²,Gobel Jeff²,Creech Katrina L.²,Strum Susan L.²,Mathis Amanda¹,Rogers Sabrinia¹,Moore Chris B.¹,Botyanszki Janos¹

Affiliation:

1. Infectious Diseases Medicines Discovery Unit, GlaxoSmithKline, 5 Moore Drive, Research Triangle Park, North Carolina 27709-3398, United States

2. Platform Technology and Science, GlaxoSmithKline, 5 Moore Drive, Research Triangle Park, North Carolina 27709-3398, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm400781h

Reference24 articles.

1. Recruitment and Activation of a Lipid Kinase by Hepatitis C Virus NS5A Is Essential for Integrity of the Membranous Replication Compartment

2. Isolation of a cDNA cLone Derived from a Blood-Borne Non-A, Non-B Viral Hepatitis Genome

3. The global burden of hepatitis C

4. Challenges in Modern Drug Discovery: A Case Study of Boceprevir, an HCV Protease Inhibitor for the Treatment of Hepatitis C Virus Infection

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