Discovery of Antitubulin Agents with Antiangiogenic Activity as Single Entities with Multitarget Chemotherapy Potential-Reference-Cited by-同舟云学术

Discovery of Antitubulin Agents with Antiangiogenic Activity as Single Entities with Multitarget Chemotherapy Potential

Published:2014-03-05 Issue:5 Volume:5 Page:480-484
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Gangjee Aleem¹,Pavana Roheeth Kumar¹,Ihnat Michael A.²,Thorpe Jessica E.²,Disch Bryan C.,Bastian Anja²,Bailey-Downs Lora C.²,Hamel Ernest³,Bai Rouli³

Affiliation:

1. Division of Medicinal Chemistry, Graduate School of Pharmaceutical Sciences, Duquesne University, Pittsburgh, Pennsylvania 15282, United States

2. Department of Pharmaceutical Sciences, University of Oklahoma College of Pharmacy, Oklahoma City, Oklahoma 73117, United States

3. Screening Technologies Branch, Developmental Therapeutics Program, Division of Cancer Treatment and Diagnosis, Frederick National Laboratory for Cancer Research, National Cancer Institute, Frederick, Maryland 21702, United States

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ml4004793

Reference16 articles.

1. Anti-angiogenic Therapy: Concept to Clinic

2. Vascular endothelial growth factor and its receptor system: physiological functions in angiogenesis and pathological roles in various diseases

3. Modes of resistance to anti-angiogenic therapy

4. Normalizing Tumor Microenvironment to Treat Cancer: Bench to Bedside to Biomarkers

5. Single Agents with Designed Combination Chemotherapy Potential: Synthesis and Evaluation of Substituted Pyrimido[4,5-b]indoles as Receptor Tyrosine Kinase and Thymidylate Synthase Inhibitors and as Antitumor Agents

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