Biologically Active Oligodeoxyribonucleotides. 5. 5‘-End-Substituted d(TGGGAG) Possesses Anti-Human Immunodeficiency Virus Type 1 Activity by Forming a G-Quadruplex Structure-Reference-Cited by-同舟云学术

Biologically Active Oligodeoxyribonucleotides. 5. 5‘-End-Substituted d(TGGGAG) Possesses Anti-Human Immunodeficiency Virus Type 1 Activity by Forming a G-Quadruplex Structure

Published:1998-08-15 Issue:19 Volume:41 Page:3655-3663
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Hotoda Hitoshi¹,Koizumi Makoto¹,Koga Rika¹,Kaneko Masakatsu¹,Momota Kenji¹,Ohmine Toshinori¹,Furukawa Hidehiko¹,Agatsuma Toshinori¹,Nishigaki Takashi¹,Sone Junko¹,Tsutsumi Shinya¹,Kosaka Toshiyuki¹,Abe Koji¹,Kimura Satoshi¹,Shimada Kaoru¹

Affiliation:

1. Exploratory Chemistry Research Laboratories, Biological Research Laboratories, and Analytical and Metabolic Research Laboratories, Sankyo Company, Ltd., 1-2-58 Hiromachi, Shinagawa-ku, Tokyo 140-8710, Japan, and The Department of Infectious Diseases, The Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108, Japan

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm970658w

Reference33 articles.

1. Biologically Active Oligodeoxyribonucleotides - IV: Anti-HIV-1 Activity of Tgggag Having Hydrophobic Substituent at Its 5′-End via Phosphodiester Linkage

2. Regulation of in vitro gene expression using antisense oligonucleotides or antisense expression plasmids transfected using starburst PAMAM dendrimers

3. Nuclease Resistance and Antisense Activity of Modified Oligonucleotides Targeted to Ha-

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