Epidoxoform: A Hydrolytically More Stable Anthracycline−Formaldehyde Conjugate Toxic to Resistant Tumor Cells-Reference-Cited by-同舟云学术

Epidoxoform: A Hydrolytically More Stable Anthracycline−Formaldehyde Conjugate Toxic to Resistant Tumor Cells

Published:1998-03-14 Issue:8 Volume:41 Page:1306-1314
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Taatjes Dylan J.¹,Fenick David J.¹,Koch Tad H.¹

Affiliation:

1. Department of Chemistry and Biochemistry, University of Colorado, Boulder, Colorado 80309-0215, and University of Colorado Cancer Center, Denver, Colorado 80262

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm970739s

Reference25 articles.

1. Production of Formaldehyde and DNA−Adriamycin or DNA−Daunomycin Adducts, Initiated through Redox Chemistry of Dithiothreitol/Iron, Xanthine Oxidase/NADH/Iron, or Glutathione/Iron

2. Redox Pathway Leading to the Alkylation of DNA by the Anthracycline, Antitumor Drugs Adriamycin and Daunomycin

3. Doxoform and Daunoform: Anthracycline−Formaldehyde Conjugates Toxic to Resistant Tumor Cells

4. Free radicals and anticancer drug resistance: Oxygen free radicals in the mechanisms of drug cytotoxicity and resistance by certain tumors

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