1. Department of Pneumonology, Medical School, University of Ioannina, Ioannina, Greece, Laboratory of Anatomy, Medical School, University of Ioannina, Ioannina, Greece, Functional Proteomics Laboratory, Department of Molecular Biology, University of Siena, Siena, Italy, Laboratory of Biochemistry, Department of Chemistry, University of Ioannina, Ioannina, Greece, and Respiratory Diseases, Department of Clinical Medicine and Immunological Sciences, University of Siena, Siena, Italy