Novel Biologically Active Nonpeptidic Inhibitors of MyristoylCoA:Protein N-Myristoyltransferase-Reference-Cited by-同舟云学术

Novel Biologically Active Nonpeptidic Inhibitors of MyristoylCoA:Protein N-Myristoyltransferase

Published:1998-02-18 Issue:6 Volume:41 Page:996-1000
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Devadas Balekudru¹,Freeman Sandra K.¹,McWherter Charles A.¹,Kishore Nandini S.¹,Lodge Jennifer K.¹,Jackson-Machelski Emily¹,Gordon Jeffrey I.¹,Sikorski James A.¹

Affiliation:

1. Department of Medicinal and Structural Chemistry, G. D. Searle and Company, 700 Chesterfield Parkway North, St. Louis, Missouri 63198, and Department of Molecular Biology and Pharmacology, Washington University School of Medicine, St. Louis, Missouri 63110

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm980001q

Reference9 articles.

1. Progress in the discovery of orally bioavailable inhibitors of HIV protease

2. Selective peptidic and peptidomimetic inhibitors of Candida albicans myristoylCoA: Protein N-myristoyltransferase: A new approach to antifungal therapy

3. Genetic studies reveal that myristoylCoA:protein N-myristoyltransferase is an essential enzyme in Candida albicans

4. Targeted gene replacement demonstrates that myristoyl-CoA: protein N-myristoyltransferase is essential for viability of Cryptococcus neoformans.

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