Engineering Protein Therapeutics: Predictive Performances of a Structure-Based Virtual Affinity Maturation Protocol
Author:
Affiliation:
1. SANOFI R&D, Centre de Recherche de Vitry/Alfortville, LGCR/SDI, 13 quai Jules Guesde - BP 14 - 94403 Vitry-sur-Seine Cedex, France
Publisher
American Chemical Society (ACS)
Subject
Library and Information Sciences,Computer Science Applications,General Chemical Engineering,General Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/ci3001474
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1. Concordance of preclinical and clinical pharmacology and toxicology of therapeutic monoclonal antibodies and fusion proteins: cell surface targets
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1. Antibody Affinity Maturation by Computational Design;Antibody Engineering;2018
2. Assessment of Solvated Interaction Energy Function for Ranking Antibody–Antigen Binding Affinities;Journal of Chemical Information and Modeling;2016-07-14
3. AB ‐Bind: Antibody binding mutational database for computational affinity predictions;Protein Science;2015-11-06
4. Applying Physics-Based Scoring to Calculate Free Energies of Binding for Single Amino Acid Mutations in Protein-Protein Complexes;PLoS ONE;2013-12-10
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