An Expeditious Route to Both Enantiomers of All Carbon Quaternary Stereocenters at C-3 Carbon of Lactams via [3,3]-Sigmatropic Rearrangement: Total Synthesis of (−)-Physostigmine-Reference-Cited by-同舟云学术

An Expeditious Route to Both Enantiomers of All Carbon Quaternary Stereocenters at C-3 Carbon of Lactams via [3,3]-Sigmatropic Rearrangement: Total Synthesis of (−)-Physostigmine

Published:2015-02-11 Issue:4 Volume:17 Page:952-955
ISSN:1523-7060
Container-title:Organic Letters
language:en
Short-container-title:Org. Lett.

Author:

Pandey Ganesh¹,Khamrai Jagadish¹,Mishra Akash¹

Affiliation:

1. Molecular Synthesis and Drug Discovery Laboratory, Centre of Biomedical Research, SGPGIMS Campus, Lucknow-226014, India

Funder

Council of Scientific and Industrial Research

Department of Science and Technology, Ministry of Science and Technology

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ol503766y

Reference91 articles.

1. Jerantinines A−G, Cytotoxic Aspidosperma Alkaloids from Tabernaemontana corymbosa

2. Total Synthesis and Biological Evaluation of Jerantinine E

3. Isolation and biological activity of aspidospermine and quebrachamine from an Aspidosperma tree source

4. Safety and Efficacy of Oral Physostigmine in the Treatment of Alzheimer Disease

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