Structure–Activity Analysis of Human Ghrelin O-Acyltransferase Reveals Chemical Determinants of Ghrelin Selectivity and Acyl Group Recognition
Author:
Affiliation:
1. Department of Chemistry, Syracuse University, Syracuse, New York 13244, United States
2. Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy, Purdue University, West Lafayette, Indiana 47907, United States
Funder
Syracuse University
Foundation for Prader-Willi Research
American Diabetes Association
March of Dimes Foundation
Division of Graduate Education
Publisher
American Chemical Society (ACS)
Subject
Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/bi5010359
Reference54 articles.
1. Ghrelin is a growth-hormone-releasing acylated peptide from stomach
2. Structure and Physiological Actions of Ghrelin
3. Profound Hypoglycemia in Starved, Ghrelin-deficient Mice Is Caused by Decreased Gluconeogenesis and Reversed by Lactate or Fatty Acids
4. Induced Ablation of Ghrelin Cells in Adult Mice Does Not Decrease Food Intake, Body Weight, or Response to High-Fat Diet
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