A New Rational Hypothesis for the Pharmacophore of the Active Metabolite of Leflunomide, a Potent Immunosuppressive Drug-Reference-Cited by-同舟云学术

A New Rational Hypothesis for the Pharmacophore of the Active Metabolite of Leflunomide, a Potent Immunosuppressive Drug

Published:1997-06-01 Issue:13 Volume:40 Page:2011-2016
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Bertolini Giorgio¹,Aquino Mario¹,Biffi Mauro¹,d'Atri Gaetano¹,Di Pierro Francesco¹,Ferrario Francesco¹,Mascagni Paolo¹,Somenzi Flavio¹,Zaliani Andrea¹,Leoni Flavio¹

Affiliation:

1. Italfarmaco Research Center, via dei Lavoratori 54, I-20092 Cinisello Balsamo, Milan, Italy

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm970039n

Reference31 articles.

1. Leflunomide (HWA 486), a novel immunomodulating compound for the treatment of autoimmune disorders and reactions leading to transplantation rejection

2. New Immunosuppressive Drugs: Mechanistic Insights and Potential Therapeutic Advances

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