Pyridophens: Binary Pyridostigmine−Aprophen Prodrugs with Differential Inhibition of Acetylcholinesterase, Butyrylcholinesterase, and Muscarinic Receptors-Reference-Cited by-同舟云学术

Pyridophens: Binary Pyridostigmine−Aprophen Prodrugs with Differential Inhibition of Acetylcholinesterase, Butyrylcholinesterase, and Muscarinic Receptors

Published:2002-01-11 Issue:4 Volume:45 Page:902-910
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Leader Haim¹,Wolfe Alan David¹,Chiang Peter K.¹,Gordon Richard K.¹

Affiliation:

1. Division of Biochemistry, Walter Reed Army Institute of Research, 503 Robert Grant Road, Silver Spring, Maryland 20910-7500

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm010196t

Reference25 articles.

1. Binary antidotes for organophosphate poisoning: aprophen analogs that are both antimuscarinics and carbamates

2. Success of pyridostigmine, physostigmine, eptastigmine and phosphotriesterase treatments in acute sarin intoxication

Cited by 22 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Novel slow-binding reversible acetylcholinesterase inhibitors based on uracil moieties for possible treatment of myasthenia gravis and protection from organophosphate poisoning;European Journal of Medicinal Chemistry;2023-01

2. Recent Advances in Synthesis of Chiral 1,2-Dihydropyridines;Acta Chimica Sinica;2021

3. Counteracting poisoning with chemical warfare nerve agents;Archives of Industrial Hygiene and Toxicology;2020-12-01

4. In silico modeling for dual inhibition of acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) enzymes in Alzheimer’s disease;Computational Biology and Chemistry;2020-10

5. Specific inhibition of acetylcholinesterase as an approach to decrease muscarinic side effects during myasthenia gravis treatment;Scientific Reports;2018-01-10