Advancements in High Throughput Biophysical Technologies: Applications for Characterization and Screening during Early Formulation Development of Monoclonal Antibodies
Author:
Affiliation:
1. Department of Formulation Sciences, MedImmune, One MedImmune Way, Gaithersburg, Maryland 20878
2. Drug Product Development, Amgen Inc., 1201 Amgen Court West, Seattle, Washington 98119
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Pharmaceutical Science,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/mp200404c
Reference108 articles.
1. Therapeutic Antibodies: Current State and Future Trends – Is a Paradigm Change Coming Soon?
2. Monoclonal antibody successes in the clinic
3. Antibody Structure, Instability, and Formulation
4. Solution Structure Determination of Monomeric Human IgA2 by X-ray and Neutron Scattering, Analytical Ultracentrifugation and Constrained Modelling: A Comparison with Monomeric Human IgA1
5. Contribution of Variable Domains to the Stability of Humanized IgG1 Monoclonal Antibodies
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