Synthesis and Quantitative Structure–Activity Relationship of Imidazotetrazine Prodrugs with Activity Independent of O6-Methylguanine-DNA-methyltransferase, DNA Mismatch Repair, and p53-Reference-Cited by-同舟云学术

Synthesis and Quantitative Structure–Activity Relationship of Imidazotetrazine Prodrugs with Activity Independent of O6-Methylguanine-DNA-methyltransferase, DNA Mismatch Repair, and p53

Published:2013-08-16 Issue:17 Volume:56 Page:7120-7132
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Pletsas Dimitrios¹,Garelnabi Elrashied A. E.¹,Li Li¹,Phillips Roger M.¹,Wheelhouse Richard T.¹

Affiliation:

1. School of Pharmacy and ‡Institute of Cancer Therapeutics, University of Bradford, Bradford, West Yorkshire BD7 1DP, U.K.

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm401121k

Reference39 articles.

1. Mechanisms of Chemoresistance to Alkylating Agents in Malignant Glioma

2. Temozolomide: Mechanisms of Action, Repair and Resistance

3. Temozolomide

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