Synthesis and Biological Evaluation of Novel Pyridazinone-Based α4 Integrin Receptor Antagonists-Reference-Cited by-同舟云学术

Synthesis and Biological Evaluation of Novel Pyridazinone-Based α4 Integrin Receptor Antagonists

Published:2006-05-09 Issue:11 Volume:49 Page:3402-3411
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Gong Yong¹,Barbay J. Kent¹,Dyatkin Alexey B.¹,Miskowski Tamara A.¹,Kimball Edward S.¹,Prouty Stephen M.¹,Fisher M. Carolyn¹,Santulli Rosemary J.¹,Schneider Craig R.¹,Wallace Nathaniel H.¹,Ballentine Scott A.¹,Hageman William E.¹,Masucci John A.¹,Maryanoff Bruce E.¹,Damiano Bruce P.¹,Andrade-Gordon Patricia¹,Hlasta Dennis J.¹,Hornby Pamela J.¹,He Wei¹

Affiliation:

1. Drug Discovery, Johnson & Johnson Pharmaceutical Research and Development, L.L.C., Welsh & McKean Roads, P.O. Box 776, Spring House, Pennsylvania 19477

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm060031q

Reference28 articles.

1. Inhibition of LFA-1/ICAM-1 and VLA-4/VCAM-1 as a therapeutic approach to inflammation and autoimmune diseases

2. α4Integrins as Therapeutic Targets in Autoimmune Disease

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