1. Institute of Bioscience and Biotechnology, National Taiwan Ocean University, Keelung, 202, Taiwan; Institute of Plant and Microbial Biology, Academia Sinica, Taipei, 115, Taiwan; Department of Biotechnology, Ming Chuan University, Taoyuan, 333, Taiwan; and Department of Food Science and Biotechnology, National Chung Hsing University, Taichung, 402, Taiwan