Semisynthesis and Kappa-Opioid Receptor Activity of Derivatives of Columbin, a Furanolactone Diterpene
Author:
Affiliation:
1. Department of Chemistry, Faculty of Arts and Sciences, Istanbul Technical University, 34469 Maslak, İstanbul, Turkey
2. Department of Medicinal Chemistry, School of Pharmacy, The University of Kansas, Lawrence, Kansas 66045, United States
Funder
American Foundation for Pharmaceutical Education
National Institute on Drug Abuse
Istanbul Teknik Üniversitesi
Türkiye Bilimsel ve Teknolojik Arastirma Kurumu
National Institute of General Medical Sciences
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Analytical Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jnatprod.7b00327
Reference36 articles.
1. A bitter diterpenoid furanolactone columbin from Calumbae Radix inhibits azoxymethane-induced rat colon carcinogenesis
2. Clerodane diterpenes: sources, structures, and biological activities
3. Chemistry and Biological Activities of the Genera Tinospora
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