Cytotoxicity, Hemolytic Toxicity, and Mechanism of Action of Pulsatilla Saponin D and Its Synthetic Derivatives-Reference-Cited by-同舟云学术

Cytotoxicity, Hemolytic Toxicity, and Mechanism of Action of Pulsatilla Saponin D and Its Synthetic Derivatives

Published:2017-11-13 Issue:3 Volume:81 Page:465-474
ISSN:0163-3864
Container-title:Journal of Natural Products
language:en
Short-container-title:J. Nat. Prod.

Author:

Chen Zhong¹²,Duan Huaqing¹,Tong Xiaohang¹,Hsu Peiling²,Han Li³,Morris-Natschke Susan L.²,Yang Shilin¹,Liu Wei²⁴,Lee Kuo-Hsiung²⁵^ORCID

Affiliation:

1. College of Pharmaceutical Science, Soochow University, 199 Ren Ai Road, Suzhou 215123, People’s Republic of China

2. Natural Products Research Laboratories, UNC Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, North Carolina 27599, United States

3. Zhang Zhongjing College of Chinese Medicine, Nanyang Institute of Technology, 80 Chang Jiang Road, Nanyang 473000, People’s Republic of China

4. Department of Pharmacology, Nanjing Medical University, Nanjing 210029, People’s Republic of China

5. Chinese Medicine Research and Development Center, China Medical University and Hospital, Taichung 401, Taiwan

Funder

National Cancer Institute

Natural Science Foundation of Jiangsu Province

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jnatprod.7b00578

Reference25 articles.

1. Strategies for the Optimization of Natural Leads to Anticancer Drugs or Drug Candidates

2. Chemical study and medical application of saponins as anti-cancer agents

3. Phenotypic analysis of established diffuse histiocytic lymphoma cell lines utilizing monoclonal antibodies and cytochemical techniques

4. Exploration of the correlation between the structure, hemolytic activity, and cytotoxicity of steroid saponins

5. Haemolytic activity, cytotoxicity and membrane cell permeabilization of semi-synthetic and natural lupane- and oleanane-type saponins

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