Jozilebomines A and B, Naphthylisoquinoline Dimers from the Congolese Liana Ancistrocladus ileboensis, with Antiausterity Activities against the PANC-1 Human Pancreatic Cancer Cell Line

Author:

Li Jun12,Seupel Raina1,Bruhn Torsten13ORCID,Feineis Doris1,Kaiser Marcel45,Brun Reto45,Mudogo Virima6,Awale Suresh7ORCID,Bringmann Gerhard1ORCID

Affiliation:

1. Institute of Organic Chemistry, University of Würzburg, Am Hubland, D-97074 Würzburg, Germany

2. State Key Laboratory Basis of Xinjiang Indigenous Medicinal Plants Resource Utilization, and Key Laboratory of Plant Resources and Chemistry of Arid Zone, Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Urumqi, 830011, People’s Republic of China

3. Federal Institute for Risk Assessment, Max-Dohrn-Straße 8-10, D-10589 Berlin, Germany

4. Swiss Tropical and Public Health Institute, Socinstrasse 57, CH-4002 Basel, Switzerland

5. University of Basel, Petersplatz 1, CH-4003 Basel, Switzerland

6. Faculté des Sciences, Université de Kinshasa, B.P. 202, Kinshasa XI, Democratic Republic of the Congo

7. Division of Natural Drug Discovery, Institute of Natural Medicine, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan

Funder

Deutsche Forschungsgemeinschaft

Japan Society for the Promotion of Science

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Analytical Chemistry

Reference73 articles.

1. aBringmann, G.; Pokorny, F.InThe Alkaloids;Cordell, G. A., Ed.Academic Press:New York, 1995; Vol.46, Chapter 4, pp127–271.

2. bBringmann, G.; Günther, C.; Ochse, M.; Schupp, O.; Tasler, S.InProgress in the Chemistry of Organic Natural Products;Herz, W.; Falk, H.; Kirby, G. W.; Moore, R. E., Eds.Springer:Wien, 2001; Vol.82, pp111–123.

3. Naphthylisoquinoline alkaloids potential drug leads

4. Naphthylisoquinoline alkaloids against malaria: evaluation of the curative potentials of dioncophylline C and dioncopeltine A against Plasmodium berghei in vivo

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