Exploring an Artificial Metabolic Route in Fusarium sporotrichioides: Production and Characterization of 7-Hydroxy T-2 Toxin-Reference-Cited by-同舟云学术

Exploring an Artificial Metabolic Route in Fusarium sporotrichioides: Production and Characterization of 7-Hydroxy T-2 Toxin

Published:2018-03-26 Issue:4 Volume:81 Page:1041-1044
ISSN:0163-3864
Container-title:Journal of Natural Products
language:en
Short-container-title:J. Nat. Prod.

Author:

Kamata Kentaro¹,Sato Hiroki²,Maeda Kazuyuki³⁴^ORCID,Furihata Kazuo⁵,Aikawa Shunichi⁶,Adachi Kentaro²,Tanaka Akira¹^ORCID,Tokai Takeshi⁴,Nakajima Yuichi³⁴^ORCID,Yoshida Yasuhiko¹²⁶,Sakuda Shohei⁵,Kimura Makoto³⁴^ORCID,Takahashi-Ando Naoko¹²⁴⁶^ORCID

Affiliation:

1. Graduate School of Engineering, Toyo University, 2100 Kujirai, Kawagoe, Saitama 350-8585, Japan

2. Graduate School of Science & Engineering, Toyo University, 2100 Kujirai, Kawagoe, Saitama 350-8585, Japan

3. Department of Biological Mechanisms and Functions, Graduate School of Bioagricultural Sciences, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, Aichi 464-8601, Japan

4. Plant and Microbial Metabolic Engineering Research Unit, RIKEN DRI, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan

5. Department of Applied Biological Chemistry, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan

6. Research Institute of Industrial Technology, Toyo University, 2100 Kujirai, Kawagoe, Saitama 350-8585, Japan

Funder

Ministry of Education, Culture, Sports, Science and Technology

Tojuro Iijima Foundation for Food Science and Technology

Inoue Enryo Foundation, Toyo University

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jnatprod.7b00398

Reference13 articles.

1. Molecular and Genetic Studies ofFusariumTrichothecene Biosynthesis: Pathways, Genes, and Evolution

2. Hydroxylations of trichothecene rings in the biosynthesis ofFusariumtrichothecenes: evolution of alternative pathways in the nivalenol chemotype

3. Isolation and nucleotide sequence of a sesquiterpene cyclase gene from the trichothecene-producing fungus Fusarium sporotrichioides

4. Fusarium Tri4 encodes a key multifunctional cytochrome P450 monooxygenase for four consecutive oxygenation steps in trichothecene biosynthesis

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