Drimane Sesquiterpenoids Noncompetitively Inhibit Human α4β2 Nicotinic Acetylcholine Receptors with Higher Potency Compared to Human α3β4 and α7 Subtypes-Reference-Cited by-同舟云学术

Drimane Sesquiterpenoids Noncompetitively Inhibit Human α4β2 Nicotinic Acetylcholine Receptors with Higher Potency Compared to Human α3β4 and α7 Subtypes

Published:2018-04-10 Issue:4 Volume:81 Page:811-817
ISSN:0163-3864
Container-title:Journal of Natural Products
language:en
Short-container-title:J. Nat. Prod.

Author:

Arias Hugo R.¹,Feuerbach Dominik²,Schmidt Bernd³,Heydenreich Matthias³,Paz Cristian⁴^ORCID,Ortells Marcelo O.⁵

Affiliation:

1. Department of Basic Sciences, California Northstate University College of Medicine, Elkgrove, California 95757, United States

2. Novartis Institutes for Biomedical Research, Basel CH-4057, Switzerland

3. Department of Chemistry, University of Potsdam, D-14469 Potsdam, Germany

4. Departamento de Química y Recursos Naturales, Universidad de La Frontera, Francisco Salazar 01145, Temuco, Chile

5. Facultad de Medicina, Universidad de Morón and CONICET, Morón 1708, Argentina

Funder

Universidad de La Frontera

Comisión Nacional de Investigación Científica y Tecnológica

College of Medicine, California Northstate University

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jnatprod.7b00893

Reference24 articles.

1. Nicotinic Receptors in Neurodegeneration

2. Nicotinic ACh receptors as therapeutic targets in CNS disorders

3. Role of Nicotinic and Muscarinic Receptors on Synaptic Plasticity and Neurological Diseases

4. Neuronal networks of nicotine addiction

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