Eupatoriopicrin Inhibits Pro-inflammatory Functions of Neutrophils via Suppression of IL-8 and TNF-alpha Production and p38 and ERK 1/2 MAP Kinases

Author:

Michalak Barbara1,Piwowarski Jakub P.1,Granica Sebastian1ORCID,Waltenberger Birgit2,Atanasov Atanas G.34ORCID,Khan Shafaat Y.56,Breuss Johannes M.5,Uhrin Pavel5,Żyżyńska-Granica Barbara7,Stojakowska Anna8,Stuppner Hermann2,Kiss Anna K.1ORCID

Affiliation:

1. Department of Pharmacognosy and Molecular Basis of Phytotherapy, Medical University of Warsaw, Warsaw 02-097, Poland

2. Institute of Pharmacy/Pharmacognosy and Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, Innsbruck 6020, Austria

3. Institute of Genetics and Animal Breeding of the Polish Academy of Science, Jastrzębiec 05-552, Poland

4. Department of Pharmacognosy, University of Vienna, Vienna 1010, Austria

5. Institute of Vascular Biology and Thrombosis Research, Center for Physiology and Pharmacology, Medical University of Vienna, Vienna 1090, Austria

6. Department of Zoology, University of Sargodha, Sargodha 40010, Pakistan

7. Department of Pharmacodynamics, Faculty of Pharmacy, Medical University of Warsaw, Warsaw 02-097, Poland

8. Institute of Pharmacology, Department of Phytochemistry, Polish Academy of Sciences, Kraków 30-024, Poland

Funder

Ministerstwo Nauki i Szkolnictwa Wyzszego

Bundesministerium f?r Wissenschaft, Forschung und Wirtschaft

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Analytical Chemistry

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