Staurosporine Derivatives Generated by Pathway Engineering in a Heterologous Host and Their Cytotoxic Selectivity-Reference-Cited by-同舟云学术

Staurosporine Derivatives Generated by Pathway Engineering in a Heterologous Host and Their Cytotoxic Selectivity

Published:2018-08-14 Issue:8 Volume:81 Page:1745-1751
ISSN:0163-3864
Container-title:Journal of Natural Products
language:en
Short-container-title:J. Nat. Prod.

Author:

Xiao Fei¹,Li Huayue¹²,Xu Mingyuan¹,Li Tong¹,Wang Ju³,Sun Chaomin²³,Hong Kui⁴,Li Wenli¹²^ORCID

Affiliation:

1. Key Laboratory of Marine Drugs, Ministry of Education of China, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, People’s Republic of China

2. Laboratory for Marine Drugs and Bioproducts of Qingdao National Laboratory for Marine Science and Technology, Qingdao 266000, People’s Republic of China

3. Key Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, People’s Republic of China

4. Key Laboratory of Combinatorial Biosynthesis and Drug Discovery, Ministry of Education of China, School of Pharmaceutical Sciences, Wuhan University, Wuhan 430071, People’s Republic of China

Funder

Shandong Province

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jnatprod.8b00103

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1. Production and biological activity of rebeccamycin, a novel antitumor agent.

2. Antimicrobial activities of indolocarbazole and bis-indole protein kinase C inhibitors.