Alkaloids Purified from Aristotelia chilensis Inhibit the Human α3β4 Nicotinic Acetylcholine Receptor with Higher Potencies Compared with the Human α4β2 and α7 Subtypes-Reference-Cited by-同舟云学术

Alkaloids Purified from Aristotelia chilensis Inhibit the Human α3β4 Nicotinic Acetylcholine Receptor with Higher Potencies Compared with the Human α4β2 and α7 Subtypes

Published:2019-07-05 Issue:7 Volume:82 Page:1953-1960
ISSN:0163-3864
Container-title:Journal of Natural Products
language:en
Short-container-title:J. Nat. Prod.

Author:

Arias Hugo R.¹,Ortells Marcelo O.²,Feuerbach Dominik³,Burgos Viviana⁴,Paz Cristian⁴^ORCID

Affiliation:

1. Department of Pharmaceutical Science, School of Pharmacy, American University of Health Sciences, Signal Hill, California 90755, United States

2. Facultad de Medicina, Universidad de Morón, and CONICET, 1708 Morón, Buenos Aires, Argentina

3. Novartis Institutes for Biomedical Research, 4001 Basel, Switzerland

4. Laboratory of Natural Products and Drug Discovery, Department of Basic Sciences, Universidad de La Frontera, 4780000 Temuco, Chile

Funder

Comisi?n Nacional de Investigaci?n Cient?fica y Tecnol?gica

Fondo Nacional de Desarrollo Cient?fico y Tecnol?gico

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jnatprod.9b00314

Reference28 articles.

1. Nicotinic ACh receptors as therapeutic targets in CNS disorders

2. Natural Compounds Interacting with Nicotinic Acetylcholine Receptors: From Low-Molecular Weight Ones to Peptides and Proteins

3. Molecular Interactions between Ligands and Nicotinic Acetylcholine Receptors Revealed by Studies with Acetylcholine Binding Proteins

4. Role of Nicotinic and Muscarinic Receptors on Synaptic Plasticity and Neurological Diseases

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