Decoding the Papain Inhibitor from Streptomyces mobaraensis as Being Hydroxylated Chymostatin Derivatives: Purification, Structure Analysis, and Putative Biosynthetic Pathway-Reference-Cited by-同舟云学术

Decoding the Papain Inhibitor from Streptomyces mobaraensis as Being Hydroxylated Chymostatin Derivatives: Purification, Structure Analysis, and Putative Biosynthetic Pathway

Published:2020-10-01 Issue:10 Volume:83 Page:2983-2995
ISSN:0163-3864
Container-title:Journal of Natural Products
language:en
Short-container-title:J. Nat. Prod.

Author:

Juettner Norbert E.¹²,Bogen Jan P.¹,Bauer Tobias A.¹,Knapp Stefan³⁴^ORCID,Pfeifer Felicitas²,Huettenhain Stefan H.¹,Meusinger Reinhard⁵,Kraemer Andreas³,Fuchsbauer Hans-Lothar¹

Affiliation:

1. The Department of Chemical Engineering and Biotechnology, University of Applied Sciences of Darmstadt, Stephanstraße 7, 64295 Darmstadt, Germany

2. The Department of Biology, Technische Universität Darmstadt, Schnittspahnstraße 10, 64287 Darmstadt, Germany

3. Institute of Pharmaceutical Chemistry, Goethe University Frankfurt, Max-von-Laue-Straße 9, 60438 Frankfurt am Main, Germany

4. Structural Genomics Consortium, Buchmann Institute for Molecular Life Sciences (BMLS), Goethe University Frankfurt, Max-von-Laue-Straße 15, 60438 Frankfurt am Main, Germany

5. The Department of Chemistry, Technische Universität Darmstadt, Alarich-Weiss-Straße 8, 64287 Darmstadt, Germany

Funder

Structural Genomics Consortium

Center for Research and Development, Darmstadt University of Applied Sciences

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jnatprod.0c00201

Reference70 articles.

1. Chemical ecology of antibiotic production by actinomycetes

2. Natural products in soil microbe interactions and evolution

3. History of Antibiotics Research

4. Molecular mechanisms of antibiotic resistance

5. Synthetic Biology Tools for Novel Secondary Metabolite Discovery in Streptomyces

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1. The Complete Genomic Sequence of Microbial Transglutaminase Producer, Streptomyces mobaraensis DSM40587;Biochemical Genetics;2023-08-02

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